While both treatments use your own blood to stimulate healing, PRF offers significant advantages. Unlike PRP, PRF creates a natural fibrin scaffold that provides structural support and gradually releases growth factors over 7-10 days (versus PRP’s 24 hours). PRF’s gentler processing preserves more healing factors and stem cells, requires no chemical additives, and provides superior structural support for addressing volume loss, sagging, and deep wrinkles—making it ideal for more natural-looking, longer-lasting results with fewer treatments.